HumanN / FORMULA REVIEW
Neo40
A dissolving tablet with citrulline and sodium nitrite inside a proprietary blend. Its blend total is not a nitrate dose.
Ownership disclosure: Better Man Report and JOYMODE share ownership. How we compare products.
OUR TAKE
Where it fits.
A different format and ingredient route from powders, chews and swallowed capsules.
THE LIMITATION
The 420 mg blend does not reveal individual citrulline or nitrite. Initial and maintenance directions differ; the product page is inconsistent about loading frequency, so confirm the box directions.
01 / INSIDE THE FORMULA
What is actually in a serving?
Amounts below are per 1 dissolving tablet. Manufacturer directions and daily cost are listed separately.
| Vitamin C | 100 mg |
|---|---|
| Vitamin B12 | 50 mcg |
| Proprietary blend (beetroot, hawthorn, citrulline, sodium nitrite) | 420 mg |
The disclosure check
Proprietary Nitric Oxide Blend 420 mg; component amounts undisclosed. Vitamins C and B12 disclosed.
- L-citrulline
- Proprietary blend; individual amount undisclosed
- Nitrate contribution
- Nitrite formula; sodium nitrite amount proprietary
A proprietary blend may disclose its total weight while keeping individual amounts private. That limits dose comparisons; it does not establish that the product has no effect.
More label details, testing & evidence
HumanN Neo40 · Sources checked September 8, 2026. Supplier specifications, certification listings and batch reports have different scopes; the notes below identify each.
Research update: Added the historical product trial and current label detail; retained the incompatible manufacturer directions as a visible limitation.
| Other ingredients | Mannitol, modified cellulose, xylitol, natural flavors, silica and stevia. The label also prints “Magnesium Vegetable, Stearate”; this appears to be malformed excipient wording, not a separately quantified magnesium nutrient.Sources: HumanN — current Neo40 Supplement Facts |
|---|---|
| Botanical and dietary details | Hawthorn is a berry extract; no marker percentage is stated. HumanN describes Neo40 as gluten-, soy-, dairy-, caffeine- and stimulant-free and non-GMO.Sources: HumanN — current Neo40 Supplement Facts · HumanN — Neo40 |
| Conflicting directions | The main product instructions say one tablet twice daily for the first 30–45 days, then daily. A gallery graphic says one daily, while FAQ wording says two every 12 hours. Confirm the pack directions with HumanN; do not infer a four-tablet routine from the inconsistent FAQ.Sources: HumanN — Neo40 |
| Historical product evidence | A small randomized placebo-controlled Neo40 study enrolled 30 adults and analyzed 29 after one lozenge twice daily for 30 days. It measured blood pressure and walking distance. This is limited historical product-level evidence; equivalence to the 2026 retail formula and clinical superiority have not been established.Sources: Biswas et al. — historical Neo40 pilot trial |
| Testing statement | HumanN claims third-party purity, potency and safety testing. No named current-lot laboratory report was verified in this review.Sources: HumanN — Neo40 |
Still unconfirmed: Individual citrulline and sodium-nitrite amounts remain proprietary; the current directions conflict is unresolved.
02 / THE EVIDENCE
Does the claim hold up?
CLAIM CHECK
What does the historical Neo40 trial establish?
A small randomized, double-blind historical Neo40 trial enrolled 30 people and analyzed 29, using one lozenge twice daily for 30 days to assess blood pressure and walking outcomes. It is product-level research, but equivalence to the current formula has not been established. It does not prove superiority over current alternatives.
Assessment: Historical product trial identified; current-formula match unverified. Source checked September 8, 2026.
Read the manufacturer’s claim in context ↗Ingredient research does not establish that this finished product improves health outcomes or outperforms another brand.
Read the research-dose guide ↗03 / ROUTINE & VALUE
What does it ask of your day?
| Reviewed version | Neo40 — 30 tablets |
|---|---|
| Package | 30 tablets |
| Label serving | 1 dissolving tablet |
| Manufacturer’s routine | Let 1 tablet dissolve in the mouth. Manufacturer specifies 1 tablet twice daily for the first 30–45 days; its maintenance directions use 1 daily. Follow the current pack. |
| Supply at that routine | 15–30 days at the manufacturer’s stated routine |
| Listed package price | $39.95 |
| Cost per label serving | $1.33 per label serving |
| Cost at the stated routine | $1.33–$2.66 per day |
| Price basis | Manufacturer one-time price for the reviewed package; shipping and tax extra. |
30 tablets provide 15 days at 2/day or 30 days at 1/day. Sodium nitrite is not nitrate. The 420 mg proprietary blend is not 420 mg of any one ingredient. The product page describes twice-daily loading, a current gallery image says one daily, and the FAQ contains another conflicting frequency. Confirm the current box instructions; the cost range describes the main page’s loading and maintenance routines.
Prices are source snapshots. Confirm the selected version and current terms before buying.
Check the current manufacturer listing ↗THE SOURCE NOTES
What this review is based on.
- Manufacturer product page
- HumanN — current Neo40 Supplement Facts
- Biswas et al. — historical Neo40 pilot trial
Published labels and source pages support this review. We have not conducted hands-on testing or a clinical comparison. Ingredient amounts are descriptive, not personal dosing advice.